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TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1)

The TRIM family of genes is largely studied because of their roles in development, differentiation and host cell anti-viral defenses; however, roles in cancer biology are emerging. Loss of heterozygosity of the TRIM3 locus in approximately 20% of human glioblastomas raised the possibility that this...

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Detalles Bibliográficos
Autores principales: Liu, Yuhui, Raheja, Radhika, Yeh, Nancy, Ciznadija, Daniel, Pedraza, Alicia M., Ozawa, Tatsuya, Hukkelhoven, Ellen, Erdjument-Bromage, Hediye, Tempst, Paul, Gauthier, Nicholas Paul, Brennan, Cameron, Holland, Eric C., Koff, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928554/
https://www.ncbi.nlm.nih.gov/pubmed/23318451
http://dx.doi.org/10.1038/onc.2012.596