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TRIM3, a tumor suppressor linked to regulation of p21(Waf1/Cip1)
The TRIM family of genes is largely studied because of their roles in development, differentiation and host cell anti-viral defenses; however, roles in cancer biology are emerging. Loss of heterozygosity of the TRIM3 locus in approximately 20% of human glioblastomas raised the possibility that this...
Autores principales: | , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928554/ https://www.ncbi.nlm.nih.gov/pubmed/23318451 http://dx.doi.org/10.1038/onc.2012.596 |