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Human immune responses to Plasmodium falciparum infection: molecular evidence for a suboptimal THαβ and TH17 bias over ideal and effective traditional TH1 immune response

BACKGROUND: Using microarray analysis, this study showed up-regulation of toll-like receptors 1, 2, 4, 7, 8, NF-κB, TNF, p38-MAPK, and MHC molecules in human peripheral blood mononuclear cells following infection with Plasmodium falciparum. METHODS: This analysis reports herein further studies based...

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Detalles Bibliográficos
Autor principal: Hu, Wan-Chung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928643/
https://www.ncbi.nlm.nih.gov/pubmed/24188121
http://dx.doi.org/10.1186/1475-2875-12-392

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