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Probiotics as efficient immunopotentiators: Translational role in cancer prevention
Accumulating evidences indicate that some diseases are triggered by abnormalities of the gut microbiota. Among these, immune-related diseases can be the promising targets for probiotcs. Several studies have proved the efficacy of probiotics for preventing such diseases including cancers, infections,...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Medknow Publications & Media Pvt Ltd
2013
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928711/ https://www.ncbi.nlm.nih.gov/pubmed/24434333 |
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author | Shida, Kan Nomoto, Koji |
author_facet | Shida, Kan Nomoto, Koji |
author_sort | Shida, Kan |
collection | PubMed |
description | Accumulating evidences indicate that some diseases are triggered by abnormalities of the gut microbiota. Among these, immune-related diseases can be the promising targets for probiotcs. Several studies have proved the efficacy of probiotics for preventing such diseases including cancers, infections, allergies, inflammatory bowel diseases and autoimmune diseases. Lactobacillus casei strain Shirota (LcS) is one of the most popular probiotics, benefits of which in health maintenance and disease control have been supported by several science-based evidences. This review summarizes human clinical trials with this probiotic against cancer development and also discusses the possible immunomodulatory mechanisms by which LcS exerts anti-cancer activity. |
format | Online Article Text |
id | pubmed-3928711 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2013 |
publisher | Medknow Publications & Media Pvt Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-39287112014-03-03 Probiotics as efficient immunopotentiators: Translational role in cancer prevention Shida, Kan Nomoto, Koji Indian J Med Res Review Article Accumulating evidences indicate that some diseases are triggered by abnormalities of the gut microbiota. Among these, immune-related diseases can be the promising targets for probiotcs. Several studies have proved the efficacy of probiotics for preventing such diseases including cancers, infections, allergies, inflammatory bowel diseases and autoimmune diseases. Lactobacillus casei strain Shirota (LcS) is one of the most popular probiotics, benefits of which in health maintenance and disease control have been supported by several science-based evidences. This review summarizes human clinical trials with this probiotic against cancer development and also discusses the possible immunomodulatory mechanisms by which LcS exerts anti-cancer activity. Medknow Publications & Media Pvt Ltd 2013-11 /pmc/articles/PMC3928711/ /pubmed/24434333 Text en Copyright: © Indian Journal of Medical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Shida, Kan Nomoto, Koji Probiotics as efficient immunopotentiators: Translational role in cancer prevention |
title | Probiotics as efficient immunopotentiators: Translational role in cancer prevention |
title_full | Probiotics as efficient immunopotentiators: Translational role in cancer prevention |
title_fullStr | Probiotics as efficient immunopotentiators: Translational role in cancer prevention |
title_full_unstemmed | Probiotics as efficient immunopotentiators: Translational role in cancer prevention |
title_short | Probiotics as efficient immunopotentiators: Translational role in cancer prevention |
title_sort | probiotics as efficient immunopotentiators: translational role in cancer prevention |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928711/ https://www.ncbi.nlm.nih.gov/pubmed/24434333 |
work_keys_str_mv | AT shidakan probioticsasefficientimmunopotentiatorstranslationalroleincancerprevention AT nomotokoji probioticsasefficientimmunopotentiatorstranslationalroleincancerprevention |