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Different effects of Atg2 and Atg18 mutations on Atg8a and Atg9 trafficking during starvation in Drosophila()

The Atg2–Atg18 complex acts in parallel to Atg8 and regulates Atg9 recycling from phagophore assembly site (PAS) during autophagy in yeast. Here we show that in Drosophila, both Atg9 and Atg18 are required for Atg8a puncta formation, unlike Atg2. Selective autophagic degradation of ubiquitinated pro...

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Detalles Bibliográficos
Autores principales: Nagy, Péter, Hegedűs, Krisztina, Pircs, Karolina, Varga, Ágnes, Juhász, Gábor
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928829/
https://www.ncbi.nlm.nih.gov/pubmed/24374083
http://dx.doi.org/10.1016/j.febslet.2013.12.012

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