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Polycomb group gene BMI1 controls invasion of medulloblastoma cells and inhibits BMP-regulated cell adhesion
BACKGROUND: Medulloblastoma is the most common intracranial childhood malignancy and a genetically heterogeneous disease. Despite recent advances, current therapeutic approaches are still associated with high morbidity and mortality. Recent molecular profiling has suggested the stratification of med...
Autores principales: | Merve, Ashirwad, Dubuc, Adrian M, Zhang, Xinyu, Remke, Marc, Baxter, Patricia A, Li, Xiao-Nan, Taylor, Michael D, Marino, Silvia |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3928978/ https://www.ncbi.nlm.nih.gov/pubmed/24460684 http://dx.doi.org/10.1186/2051-5960-2-10 |
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