A Multi-Site Validation in India of the Line Probe Assay for the Rapid Diagnosis of Multi-Drug Resistant Tuberculosis Directly from Sputum Specimens

Rifampicin (R) and isoniazid (H) are key first-line anti-tuberculosis drugs. Failure to detect resistance to these two drugs early results in treatment failure and poor clinical outcomes. The study purpose was to validate the use of the GenoType MTBDRplus line probe assay (LPA) to detect resistance...

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Detalles Bibliográficos
Autores principales: Raizada, Neeraj, Sachdeva, K. S., Chauhan, D. S., Malhotra, Bharti, Reddy, Kishore, Dave, P. V., Mundade, Yamuna, Patel, Pranav, Ramachandran, Ranjani, Das, Ram, Solanki, Rajesh, Wares, Douglas Fraser, Sahu, Suvanand, O'Brien, Rick, Paramasivan, C. N., Dewan, Puneet K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929364/
https://www.ncbi.nlm.nih.gov/pubmed/24586360
http://dx.doi.org/10.1371/journal.pone.0088626

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