VEGF-D-induced draining lymphatic enlargement and tumor lymphangiogenesis promote lymph node metastasis in a xenograft model of ovarian carcinoma

BACKGROUND: Vascular endothelial growth factor (VEGF)-D has been shown to promote lymph node metastasis in several cancers. Although generally overexpressed in ovarian carcinoma, its role in nodal dissemination of this cancer is unclear. To clarify the role of VEGF-D and the underlying molecular mec...

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Detalles Bibliográficos
Autores principales: Du, Li-Cheng, Chen, Xian-Cheng, Wang, Dong, Wen, Yan-Jun, Wang, Chun-Ting, Wang, Xue-Mei, Kan, Bing, Wei, Yu-Quan, Zhao, Xia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929486/
https://www.ncbi.nlm.nih.gov/pubmed/24502459
http://dx.doi.org/10.1186/1477-7827-12-14

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