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DNA Aptamers against Exon v10 of CD44 Inhibit Breast Cancer Cell Migration

CD44 adhesion molecules are expressed in many breast cancer cells and have been demonstrated to play a key role in regulating malignant phenotypes such as growth, migration, and invasion. CD44 is an integral transmembrane protein encoded by a single 20-exon gene. The diversity of the biological func...

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Detalles Bibliográficos
Autores principales: Iida, Joji, Clancy, Rebecca, Dorchak, Jesse, Somiari, Richard I., Somiari, Stella, Cutler, Mary Lou, Mural, Richard J., Shriver, Craig D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929491/
https://www.ncbi.nlm.nih.gov/pubmed/24586375
http://dx.doi.org/10.1371/journal.pone.0088712