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The Kick-In System: A Novel Rapid Knock-In Strategy
Knock-in mouse models have contributed tremendously to our understanding of human disorders. However, generation of knock-in animals requires a significant investment of time and effort. We addressed this problem by developing a novel knock-in system that circumvents several traditional challenges b...
Autores principales: | Tomonoh, Yuko, Deshimaru, Masanobu, Araki, Kimi, Miyazaki, Yasuhiro, Arasaki, Tomoko, Tanaka, Yasuyoshi, Kitamura, Haruna, Mori, Fumiaki, Wakabayashi, Koichi, Yamashita, Sayaka, Saito, Ryo, Itoh, Masayuki, Uchida, Taku, Yamada, Junko, Migita, Keisuke, Ueno, Shinya, Kitaura, Hiroki, Kakita, Akiyoshi, Lossin, Christoph, Takano, Yukio, Hirose, Shinichi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929540/ https://www.ncbi.nlm.nih.gov/pubmed/24586341 http://dx.doi.org/10.1371/journal.pone.0088549 |
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