Genetic variants conferring susceptibility to Alzheimer’s disease in the general population; do they also predispose to dementia in Down’s syndrome

BACKGROUND: Down’s syndrome (DS) is caused by either complete or partial triplication of chromosome 21, affecting approximately 1/1000 live births, and it is widely accepted that individuals with DS are more likely to develop dementia of Alzheimer’s disease (DAD) compared with the general population...

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Detalles Bibliográficos
Autores principales: Patel, Ashok, Rees, Simon D, Kelly, M Ann, Bain, Stephen C, Barnett, Anthony H, Prasher, Anisha, Arshad, Humaria, Prasher, Vee P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929558/
https://www.ncbi.nlm.nih.gov/pubmed/24438528
http://dx.doi.org/10.1186/1756-0500-7-42

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