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Miz1 Deficiency in the Mammary Gland Causes a Lactation Defect by Attenuated Stat5 Expression and Phosphorylation

Miz1 is a zinc finger transcription factor with an N-terminal POZ domain. Complexes with Myc, Bcl-6 or Gfi-1 repress expression of genes like Cdkn2b (p15(Ink4)) or Cdkn1a (p21(Cip1)). The role of Miz1 in normal mammary gland development has not been addressed so far. Conditional knockout of the Miz1...

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Detalles Bibliográficos
Autores principales:	Sanz-Moreno, Adrián, Fuhrmann, David, Wolf, Elmar, von Eyss, Björn, Eilers, Martin, Elsässer, Hans-Peter
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929623/ https://www.ncbi.nlm.nih.gov/pubmed/24586582 http://dx.doi.org/10.1371/journal.pone.0089187

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