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Iron Chelation by Deferoxamine Prevents Renal Interstitial Fibrosis in Mice with Unilateral Ureteral Obstruction
Renal fibrosis plays an important role in the onset and progression of chronic kidney diseases (CKD). Although several mechanisms underlying renal fibrosis and candidate drugs for its treatment have been identified, the effect of iron chelator on renal fibrosis remains unclear. In the present study,...
Autores principales: | Ikeda, Yasumasa, Ozono, Iori, Tajima, Soichiro, Imao, Mizuki, Horinouchi, Yuya, Izawa-Ishizawa, Yuki, Kihira, Yoshitaka, Miyamoto, Licht, Ishizawa, Keisuke, Tsuchiya, Koichiro, Tamaki, Toshiaki |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929716/ https://www.ncbi.nlm.nih.gov/pubmed/24586712 http://dx.doi.org/10.1371/journal.pone.0089355 |
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