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Synthetic LPETG-Containing Peptide Incorporation in the Staphylococcus aureus Cell-Wall in a Sortase A- and Growth Phase-Dependent Manner
The majority of Staphylococcus aureus virulence- and colonization-associated surface proteins contain a pentapeptide recognition motif (LPXTG). This motif can be recognized and cleaved by sortase A (SrtA) which is a membrane-bound transpeptidase. After cleavage these proteins are covalently incorpor...
Autores principales: | Hansenová Maňásková, Silvie, Nazmi, Kamran, van Belkum, Alex, Bikker, Floris J., van Wamel, Willem J. B., Veerman, Enno C. I. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929722/ https://www.ncbi.nlm.nih.gov/pubmed/24586638 http://dx.doi.org/10.1371/journal.pone.0089260 |
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