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Metformin anti-tumor effect via disruption of the MID1 translational regulator complex and AR downregulation in prostate cancer cells
BACKGROUND: Metformin is an approved drug prescribed for diabetes. Its role as an anti-cancer agent has drawn significant attention because of its minimal side effects and low cost. However, its mechanism of anti-tumour action has not yet been fully clarified. METHODS: The effect on cell growth was...
Autores principales: | Demir, Ummuhan, Koehler, Andrea, Schneider, Rainer, Schweiger, Susann, Klocker, Helmut |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929757/ https://www.ncbi.nlm.nih.gov/pubmed/24484909 http://dx.doi.org/10.1186/1471-2407-14-52 |
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