Transdifferentiation of lung adenocarcinoma in mice with Lkb1 deficiency to squamous cell carcinoma

Lineage transition in adenocarcinoma (ADC) and squamous cell carcinoma (SCC) of non-small cell lung cancer, as implicated by clinical observation of mixed ADC and SCC pathologies in adenosquamous cell carcinoma, remains a fundamental yet unsolved question. Here we provide in vivo evidence showing th...

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Detalles Bibliográficos
Autores principales: Han, Xiangkun, Li, Fuming, Fang, Zhaoyuan, Gao, Yijun, Li, Fei, Fang, Rong, Yao, Shun, Sun, Yihua, Li, Li, Zhang, Wenjing, Ma, Huimin, Xiao, Qian, Ge, Gaoxiang, Fang, Jing, Wang, Hongda, Zhang, Lei, Wong, Kwok-kin, Chen, Haiquan, Hou, Yingyong, Ji, Hongbin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929783/
https://www.ncbi.nlm.nih.gov/pubmed/24531128
http://dx.doi.org/10.1038/ncomms4261

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