IRF8 suppresses pathological cardiac remodelling by inhibiting calcineurin signalling

Interferon regulatory factor 8 (IRF8) is known to affect the innate immune response, for example, by regulating the differentiation and function of immune cells. However, whether IRF8 can influence cardiac hypertrophy is unknown. Here we show that IRF8 levels are decreased in human dilated/hypertrop...

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Detalles Bibliográficos
Autores principales: Jiang, Ding-Sheng, Wei, Xiang, Zhang, Xiao-Fei, Liu, Yu, Zhang, Yan, Chen, Ke, Gao, Lu, Zhou, Heng, Zhu, Xue-Hai, Liu, Peter P., Bond Lau, Wayne, Ma, Xinliang, Zou, Yunzeng, Zhang, Xiao-Dong, Fan, Guo-Chang, Li, Hongliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Pub. Group 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929801/
https://www.ncbi.nlm.nih.gov/pubmed/24526256
http://dx.doi.org/10.1038/ncomms4303

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