Mutation frequencies of GNAQ, GNA11, BAP1, SF3B1, EIF1AX and TERT in uveal melanoma: detection of an activating mutation in the TERT gene promoter in a single case of uveal melanoma

BACKGROUND: Uveal melanoma is the most frequent primary tumour of the eye. It is molecularly clearly distinct from cutaneous melanoma and shows a different pattern of driver mutations. The influence of sunlight ultraviolet (UV) exposure on the aetiology of uveal melanoma is a matter of debate. The r...

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Detalles Bibliográficos
Autores principales: Dono, M, Angelini, G, Cecconi, M, Amaro, A, Esposito, A I, Mirisola, V, Maric, I, Lanza, F, Nasciuti, F, Viaggi, S, Gualco, M, Bandelloni, R, Truini, M, Coviello, D A, Zupo, S, Mosci, C, Pfeffer, U
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Genetics and Genomics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929883/
https://www.ncbi.nlm.nih.gov/pubmed/24423917
http://dx.doi.org/10.1038/bjc.2013.804

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