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CD44 targets Na(+)/H(+) exchanger 1 to mediate MDA-MB-231 cells' metastasis via the regulation of ERK1/2

BACKGROUND: CD44, a transmembrane glycoprotein expressed in a variety of cells and tissues, has been implicated in tumour metastasis. But the molecular mechanisms of CD44-mediated tumour cell metastasis remain to be elucidated. METHODS: The downregulation of CD44 was determined by immunofluorescence...

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Detalles Bibliográficos
Autores principales:	Chang, G, Wang, J, Zhang, H, Zhang, Y, Wang, C, Xu, H, Lin, Y, Ma, L, Li, Q, Pang, T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2014
Materias:	Translational Therapeutics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929887/ https://www.ncbi.nlm.nih.gov/pubmed/24434427 http://dx.doi.org/10.1038/bjc.2013.809

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