Hypoxia triggers a Nur77–β-catenin feed-forward loop to promote the invasive growth of colon cancer cells

BACKGROUND: β-Catenin is a potent oncogenic protein in colorectal cancer (CRC), but the targets and regulation of this important signalling molecule are not completely understood. Hypoxia is a prominent feature of solid tumours that contributes to cancer progression. METHODS: Here, we analysed the r...

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Detalles Bibliográficos
Autores principales: To, S K Y, Zeng, W-J, Zeng, J-Z, Wong, A S T
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2014
Materias:
Molecular Diagnostics
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929893/
https://www.ncbi.nlm.nih.gov/pubmed/24423919
http://dx.doi.org/10.1038/bjc.2013.816

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929893/
https://www.ncbi.nlm.nih.gov/pubmed/24423919
http://dx.doi.org/10.1038/bjc.2013.816

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