Muscle insulin sensitivity and glucose metabolism are controlled by the intrinsic muscle clock()

Circadian rhythms control metabolism and energy homeostasis, but the role of the skeletal muscle clock has never been explored. We generated conditional and inducible mouse lines with muscle-specific ablation of the core clock gene Bmal1. Skeletal muscles from these mice showed impaired insulin-stim...

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Detalles Bibliográficos
Autores principales: Dyar, Kenneth A., Ciciliot, Stefano, Wright, Lauren E., Biensø, Rasmus S., Tagliazucchi, Guidantonio M., Patel, Vishal R., Forcato, Mattia, Paz, Marcia I.P., Gudiksen, Anders, Solagna, Francesca, Albiero, Mattia, Moretti, Irene, Eckel-Mahan, Kristin L., Baldi, Pierre, Sassone-Corsi, Paolo, Rizzuto, Rosario, Bicciato, Silvio, Pilegaard, Henriette, Blaauw, Bert, Schiaffino, Stefano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929910/
https://www.ncbi.nlm.nih.gov/pubmed/24567902
http://dx.doi.org/10.1016/j.molmet.2013.10.005

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