Cargando…

Central action of FGF19 reduces hypothalamic AGRP/NPY neuron activity and improves glucose metabolism()

Tight control of glucose excursions has been a long-standing goal of treatment for patients with type 2 diabetes mellitus in order to ameliorate the morbidity and mortality associated with hyperglycemia. Fibroblast growth factor (FGF) 19 is a hormone-like enterokine released postprandially that emer...

Descripción completa

Detalles Bibliográficos
Autores principales:	Marcelin, Geneviève, Jo, Young-Hwan, Li, Xiaosong, Schwartz, Gary J., Zhang, Ying, Dun, Nae J., Lyu, Rong-Ming, Blouet, Clémence, Chang, Jaw K., Chua, Streamson
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2013
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3929918/ https://www.ncbi.nlm.nih.gov/pubmed/24567901 http://dx.doi.org/10.1016/j.molmet.2013.10.002

Ejemplares similares

A gut–brain axis regulating glucose metabolism mediated by bile acids and competitive fibroblast growth factor actions at the hypothalamus
por: Liu, Shunmei, et al.
Publicado: (2017)

Sustained inhibition of NPY/AgRP neuronal activity by FGF1
por: Hwang, Eunsang, et al.
Publicado: (2022)

The gut signals to AGRP-expressing cells of the pituitary to control glucose homeostasis
por: Liu, Shun-Mei, et al.
Publicado: (2023)

Direct and indirect effects of liraglutide on hypothalamic POMC and NPY/AgRP neurons – Implications for energy balance and glucose control
por: He, Zhenyan, et al.
Publicado: (2019)

Proliferative Hypothalamic Neurospheres Express NPY, AGRP, POMC, CART and Orexin-A and Differentiate to Functional Neurons
por: Sousa-Ferreira, Lígia, et al.
Publicado: (2011)

Diet composition, not calorie intake, rapidly alters intrinsic excitability of hypothalamic AgRP/NPY neurons in mice
por: Wei, Wei, et al.
Publicado: (2015)

NPY mediates the rapid feeding and glucose metabolism regulatory functions of AgRP neurons
por: Engström Ruud, Linda, et al.
Publicado: (2020)

mTORC1 in AGRP neurons integrates exteroceptive and interoceptive food-related cues in the modulation of adaptive energy expenditure in mice
por: Burke, Luke K, et al.
Publicado: (2017)

Enhanced Ghrelin Levels and Hypothalamic Orexigenic AgRP and NPY Neuropeptide Expression in Models of Jejuno-Colonic Short Bowel Syndrome
por: Gillard, Laura, et al.
Publicado: (2016)

Sustained NPY signaling enables AgRP neurons to drive feeding
por: Chen, Yiming, et al.
Publicado: (2019)

Cholinergic neurons in the dorsomedial hypothalamus regulate mouse brown adipose tissue metabolism
por: Jeong, Jae Hoon, et al.
Publicado: (2015)

Antagonistic modulation of NPY/AgRP and POMC neurons in the arcuate nucleus by noradrenalin
por: Paeger, Lars, et al.
Publicado: (2017)

Identification of a Loss-of-Function Mutation in Ube2l6 Associated With Obesity Resistance
por: Marcelin, Genevieve, et al.
Publicado: (2013)

SUN-LB007 The Mouse AgRP Gene Has Three Promoters: Differential Regulation by Nutritional States
por: Ifebi, Bruno, et al.
Publicado: (2019)

Cellular and synaptic reorganization of arcuate NPY/AgRP and POMC neurons after exercise
por: He, Zhenyan, et al.
Publicado: (2018)

Local Drd1-neurons input to subgroups of arcuate AgRP/NPY-neurons
por: Chadwick, Sean R., et al.
Publicado: (2022)

Unlike calorie restriction, Roux-en-Y gastric bypass surgery does not increase hypothalamic AgRP and NPY in mice on a high-fat diet
por: Patkar, Presheet P., et al.
Publicado: (2019)

AgRP/NPY Neuron Excitability Is Modulated by Metabotropic Glutamate Receptor 1 During Fasting
por: Laing, Brenton T., et al.
Publicado: (2018)

Central α-Klotho Suppresses NPY/AgRP Neuron Activity and Regulates Metabolism in Mice
por: Landry, Taylor, et al.
Publicado: (2020)

Nutrient sensing in the nucleus of the solitary tract mediates non-aversive suppression of feeding via inhibition of AgRP neurons
por: Tsang, Anthony H., et al.
Publicado: (2020)

A Small Potassium Current in AgRP/NPY Neurons Regulates Feeding Behavior and Energy Metabolism
por: He, Yanlin, et al.
Publicado: (2016)

Fasting Upregulates npy, agrp, and ghsr Without Increasing Ghrelin Levels in Zebrafish (Danio rerio) Larvae
por: Opazo, Rafael, et al.
Publicado: (2019)

Altered features of neurotransmitters: NPY, α-MSH, and AgRP in type 2 diabetic patients with hypertension
por: Li, Baoxin, et al.
Publicado: (2020)

The Brain–Liver Connection Between BDNF and Glucose Control
por: Jo, Young-Hwan, et al.
Publicado: (2013)

Phosphoinositide 3-Kinase Is Integral for the Acute Activity of Leptin and Insulin in Male Arcuate NPY/AgRP Neurons
por: Huang, Yiru, et al.
Publicado: (2018)

Cannabinoid type 1 receptor-containing axons innervate NPY/AgRP neurons in the mouse arcuate nucleus
por: Morozov, Yury M., et al.
Publicado: (2017)

Investigating the NPY/AgRP/GABA to GnRH Neuron Circuit in Prenatally Androgenized PCOS-Like Mice
por: Marshall, Christopher J, et al.
Publicado: (2020)

p53 and energy balance: meeting hypothalamic AgRP neurons
por: Al-Massadi, Omar, et al.
Publicado: (2018)

Optogenetic stimulation of the liver-projecting melanocortinergic pathway promotes hepatic glucose production
por: Kwon, Eunjin, et al.
Publicado: (2020)

ARC(AgRP/NPY) Neuron Activity Is Required for Acute Exercise-Induced Food Intake in Un-Trained Mice
por: Bunner, Wyatt, et al.
Publicado: (2020)

Modified Peptide YY Molecule Attenuates the Activity of NPY/AgRP Neurons and Reduces Food Intake in Male Mice
por: Jones, Edward S, et al.
Publicado: (2019)

Direct versus indirect actions of ghrelin on hypothalamic NPY neurons
por: Hashiguchi, Hiroshi, et al.
Publicado: (2017)

Dieting reverses histone methylation and hypothalamic AgRP regulation in obese rats
por: Rapps, Kayla, et al.
Publicado: (2023)

Time and metabolic state-dependent effects of GLP-1R agonists on NPY/AgRP and POMC neuronal activity in vivo
por: Dong, Yanbin, et al.
Publicado: (2021)

CRISPR knockdown of Kcnq3 attenuates the M-current and increases excitability of NPY/AgRP neurons to alter energy balance
por: Stincic, Todd L., et al.
Publicado: (2021)

Duodenal Lipid Sensing Activates Vagal Afferents to Regulate Non-Shivering Brown Fat Thermogenesis in Rats
por: Blouet, Clémence, et al.
Publicado: (2012)

SUN-LB083 Functional Role of Arcuate Nucleus NPY/AgRP Neurons in the GnRH Circuit Regulating LH Secretion
por: Coutinho, Eulalia, et al.
Publicado: (2019)

Hypothalamic KLF4 mediates leptin's effects on food intake via AgRP
por: Imbernon, Monica, et al.
Publicado: (2014)

Somato-Dendritic Localization and Signaling by Leptin Receptors in Hypothalamic POMC and AgRP Neurons
por: Ha, Sangdeuk, et al.
Publicado: (2013)

Dlx1/2 and Otp coordinate the production of hypothalamic GHRH- and AgRP-neurons
por: Lee, Bora, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_pfj0qruk93k97f7cslccv073oe