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Comparative analysis of the activation of unfolded protein response by spike proteins of severe acute respiratory syndrome coronavirus and human coronavirus HKU1

BACKGROUND: Whereas severe acute respiratory syndrome (SARS) coronavirus (SARS-CoV) is associated with severe disease, human coronavirus HKU1 (HCoV-HKU1) commonly circulates in the human populations causing generally milder illness. Spike (S) protein of SARS-CoV activates the unfolded protein respon...

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Detalles Bibliográficos
Autores principales:	Siu, Kam-Leung, Chan, Ching-Ping, Kok, Kin-Hang, Woo, Patrick C-Y, Jin, Dong-Yan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930072/ https://www.ncbi.nlm.nih.gov/pubmed/24410900 http://dx.doi.org/10.1186/2045-3701-4-3

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