Cargando…
Protection against collagen-induced arthritis in mice afforded by the parasitic worm product, ES-62, is associated with restoration of the levels of interleukin-10-producing B cells and reduced plasma cell infiltration of the joints
We have previously reported that ES-62, a molecule secreted by the parasitic filarial nematode Acanthocheilonema viteae, protects mice from developing collagen-induced arthritis (CIA). Together with increasing evidence that worm infection may protect against autoimmune conditions, this raises the po...
Autores principales: | Rodgers, David T, Pineda, Miguel A, McGrath, Mairi A, Al-Riyami, Lamyaa, Harnett, William, Harnett, Margaret M |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley & Sons Ltd
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930382/ https://www.ncbi.nlm.nih.gov/pubmed/24708419 http://dx.doi.org/10.1111/imm.12208 |
Ejemplares similares
-
The Parasitic Worm Product ES-62 Targets Myeloid Differentiation Factor 88–Dependent Effector Mechanisms to Suppress Antinuclear Antibody Production and Proteinuria in MRL/lpr Mice
por: Rodgers, David T, et al.
Publicado: (2015) -
ES‐62 Protects Against Collagen‐Induced Arthritis by Resetting Interleukin‐22 Toward Resolution of Inflammation in the Joints
por: Pineda, Miguel A., et al.
Publicado: (2014) -
IL-33/ST2 signalling and crosstalk with FcεRI and TLR4 is targeted by the parasitic worm product, ES-62
por: Ball, Dimity H., et al.
Publicado: (2018) -
Designing Anti-inflammatory
Drugs from Parasitic Worms:
A Synthetic Small Molecule Analogue of the Acanthocheilonema
viteae Product ES-62 Prevents Development of Collagen-Induced
Arthritis
por: Al-Riyami, Lamyaa, et al.
Publicado: (2013) -
Protective effect of small molecule analogues of the Acanthocheilonema viteae secreted product ES-62 on oxazolone-induced ear inflammation
por: Al-Riyami, Lamyaa, et al.
Publicado: (2015)