Identification of novel candidate compounds targeting TrkB to induce apoptosis in neuroblastoma

Neuroblastoma (NB) is one of the most frequent solid tumors in children and its prognosis is still poor. The neurotrophin receptor TrkB and its ligand brain-derived neurotrophic factor (BDNF) are expressed at high levels in high-risk NBs and are involved in defining the poor prognosis of the patient...

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Detalles Bibliográficos
Autores principales: Nakamura, Yohko, Suganami, Akiko, Fukuda, Mayu, Hasan, Md Kamrul, Yokochi, Tomoki, Takatori, Atsushi, Satoh, Shunpei, Hoshino, Tyuji, Tamura, Yutaka, Nakagawara, Akira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley & Sons Ltd. 2014
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930387/
https://www.ncbi.nlm.nih.gov/pubmed/24403123
http://dx.doi.org/10.1002/cam4.175

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