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Sinonasal inhalation of tobramycin vibrating aerosol in cystic fibrosis patients with upper airway Pseudomonas aeruginosa colonization: results of a randomized, double-blind, placebo-controlled pilot study

RATIONALE: In cystic fibrosis (CF), the paranasal sinuses are sites of first and persistent colonization by pathogens such as Pseudomonas aeruginosa. Pathogens subsequently descend to the lower airways, with P. aeruginosa remaining the primary cause of premature death in patients with the inherited...

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Detalles Bibliográficos
Autores principales: Mainz, Jochen G, Schädlich, Katja, Schien, Claudia, Michl, Ruth, Schelhorn-Neise, Petra, Koitschev, Assen, Koitschev, Christiane, Keller, Peter M, Riethmüller, Joachim, Wiedemann, Baerbel, Beck, James F
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930477/
https://www.ncbi.nlm.nih.gov/pubmed/24596456
http://dx.doi.org/10.2147/DDDT.S54064

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