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Sinonasal inhalation of tobramycin vibrating aerosol in cystic fibrosis patients with upper airway Pseudomonas aeruginosa colonization: results of a randomized, double-blind, placebo-controlled pilot study
RATIONALE: In cystic fibrosis (CF), the paranasal sinuses are sites of first and persistent colonization by pathogens such as Pseudomonas aeruginosa. Pathogens subsequently descend to the lower airways, with P. aeruginosa remaining the primary cause of premature death in patients with the inherited...
Autores principales: | Mainz, Jochen G, Schädlich, Katja, Schien, Claudia, Michl, Ruth, Schelhorn-Neise, Petra, Koitschev, Assen, Koitschev, Christiane, Keller, Peter M, Riethmüller, Joachim, Wiedemann, Baerbel, Beck, James F |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930477/ https://www.ncbi.nlm.nih.gov/pubmed/24596456 http://dx.doi.org/10.2147/DDDT.S54064 |
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