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A Virtual Infection Model Quantifies Innate Effector Mechanisms and Candida albicans Immune Escape in Human Blood

Candida albicans bloodstream infection is increasingly frequent and can result in disseminated candidiasis associated with high mortality rates. To analyze the innate immune response against C. albicans, fungal cells were added to human whole-blood samples. After inoculation, C. albicans started to...

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Detalles Bibliográficos
Autores principales: Hünniger, Kerstin, Lehnert, Teresa, Bieber, Kristin, Martin, Ronny, Figge, Marc Thilo, Kurzai, Oliver
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930496/
https://www.ncbi.nlm.nih.gov/pubmed/24586131
http://dx.doi.org/10.1371/journal.pcbi.1003479