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Arf4 Is Required for Mammalian Development but Dispensable for Ciliary Assembly
The primary cilium is a sensory organelle, defects in which cause a wide range of human diseases including retinal degeneration, polycystic kidney disease and birth defects. The sensory functions of cilia require specific receptors to be targeted to the ciliary subdomain of the plasma membrane. Arf4...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930517/ https://www.ncbi.nlm.nih.gov/pubmed/24586199 http://dx.doi.org/10.1371/journal.pgen.1004170 |