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Arf4 Is Required for Mammalian Development but Dispensable for Ciliary Assembly

The primary cilium is a sensory organelle, defects in which cause a wide range of human diseases including retinal degeneration, polycystic kidney disease and birth defects. The sensory functions of cilia require specific receptors to be targeted to the ciliary subdomain of the plasma membrane. Arf4...

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Detalles Bibliográficos
Autores principales: Follit, John A., San Agustin, Jovenal T., Jonassen, Julie A., Huang, Tingting, Rivera-Perez, Jaime A., Tremblay, Kimberly D., Pazour, Gregory J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930517/
https://www.ncbi.nlm.nih.gov/pubmed/24586199
http://dx.doi.org/10.1371/journal.pgen.1004170

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