Cargando…

Arf4 Is Required for Mammalian Development but Dispensable for Ciliary Assembly

The primary cilium is a sensory organelle, defects in which cause a wide range of human diseases including retinal degeneration, polycystic kidney disease and birth defects. The sensory functions of cilia require specific receptors to be targeted to the ciliary subdomain of the plasma membrane. Arf4...

Descripción completa

Detalles Bibliográficos
Autores principales:	Follit, John A., San Agustin, Jovenal T., Jonassen, Julie A., Huang, Tingting, Rivera-Perez, Jaime A., Tremblay, Kimberly D., Pazour, Gregory J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930517/ https://www.ncbi.nlm.nih.gov/pubmed/24586199 http://dx.doi.org/10.1371/journal.pgen.1004170

Ejemplares similares

Deletion of IFT20 in the mouse kidney causes misorientation of the mitotic spindle and cystic kidney disease
por: Jonassen, Julie A., et al.
Publicado: (2008)

The Golgin GMAP210/TRIP11 Anchors IFT20 to the Golgi Complex
por: Follit, John A., et al.
Publicado: (2008)

Intraflagellar transport is essential for mammalian spermiogenesis but is absent in mature sperm
por: San Agustin, Jovenal T., et al.
Publicado: (2015)

The cytoplasmic tail of fibrocystin contains a ciliary targeting sequence
por: Follit, John A., et al.
Publicado: (2010)

Pericentrin forms a complex with intraflagellar transport proteins and polycystin-2 and is required for primary cilia assembly
por: Jurczyk, Agata, et al.
Publicado: (2004)

Loss of Arf4 causes severe degeneration of the exocrine pancreas but not cystic kidney disease or retinal degeneration
por: Pearring, Jillian N., et al.
Publicado: (2017)

The role of intraflagellar transport proteins in ciliary assembly and function
por: Pazour, GJ
Publicado: (2012)

Genetic link between renal birth defects and congenital heart disease
por: San Agustin, Jovenal T., et al.
Publicado: (2016)

Erratum: Genetic link between renal birth defects and congenital heart disease
por: San Agustin, Jovenal T., et al.
Publicado: (2016)

Functional analysis of an individual IFT protein: IFT46 is required for transport of outer dynein arms into flagella
por: Hou, Yuqing, et al.
Publicado: (2007)

The ciliary transition zone functions in cell adhesion but is dispensable for axoneme assembly in C. elegans
por: Schouteden, Clementine, et al.
Publicado: (2015)

Ubiquitylation of BBSome is required for ciliary assembly and signaling
por: Chiuso, Francesco, et al.
Publicado: (2023)

Retinoic acid is dispensable for meiotic initiation but required for spermiogenesis in the mammalian testis
por: Kirsanov, Oleksandr, et al.
Publicado: (2023)

CFAP54 is required for proper ciliary motility and assembly of the central pair apparatus in mice
por: McKenzie, Casey W., et al.
Publicado: (2015)

hemingway is required for sperm flagella assembly and ciliary motility in Drosophila
por: Soulavie, Fabien, et al.
Publicado: (2014)

The Arf GEF GBF1 integrates inputs from its product, Arf4·GTP, and the Golgi influx of sensory membrane cargo to activate Arf4 in ciliary trafficking
por: Deretic, D, et al.
Publicado: (2015)

The DHC1b (DHC2) Isoform of Cytoplasmic Dynein Is Required for Flagellar Assembly
por: Pazour, Gregory J., et al.
Publicado: (1999)

E3 ubiquitin ligase Wwp1 regulates ciliary dynamics of the Hedgehog receptor Smoothened
por: Lv, Bo, et al.
Publicado: (2021)

Arf GTPases Are Required for the Establishment of the Pre-Assembly Compartment in the Early Phase of Cytomegalovirus Infection
por: Pavišić, Valentino, et al.
Publicado: (2021)

Identification of a Guanine Nucleotide Exchange Factor for Arf3, the Yeast Orthologue of Mammalian Arf6
por: Gillingham, Alison K., et al.
Publicado: (2007)

Disruption of Mks1 localization to the mother centriole causes cilia defects and developmental malformations in Meckel-Gruber syndrome
por: Cui, Cheng, et al.
Publicado: (2011)

The elongation factor Elof1 is required for mammalian gastrulation
por: Tellier, Adam P., et al.
Publicado: (2019)

The CSC is required for complete radial spoke assembly and wild-type ciliary motility
por: Dymek, Erin E., et al.
Publicado: (2011)

Interaction of INPP5E with ARL13B is essential for its ciliary membrane retention but dispensable for its ciliary entry
por: Qiu, Hantian, et al.
Publicado: (2021)

The ARF GAPs ELMOD1 and ELMOD3 act at the Golgi and cilia to regulate ciliogenesis and ciliary protein traffic
por: Turn, Rachel E., et al.
Publicado: (2022)

Initial ciliary assembly in Chlamydomonas requires Arp2/3 complex–dependent endocytosis
por: Bigge, Brae M., et al.
Publicado: (2023)

Hazara Nairovirus Requires COPI Components in both Arf1-Dependent and Arf1-Independent Stages of Its Replication Cycle
por: Fuller, J., et al.
Publicado: (2020)

Transition fibre protein FBF1 is required for the ciliary entry of assembled intraflagellar transport complexes
por: Wei, Qing, et al.
Publicado: (2013)

Chlamydomonas IFT25 is dispensable for flagellar assembly but required to export the BBSome from flagella
por: Dong, Bin, et al.
Publicado: (2017)

HIV-1 requires Arf6-mediated membrane dynamics to efficiently enter and infect T lymphocytes
por: García-Expósito, Laura, et al.
Publicado: (2011)

CCDC103 mutations cause primary ciliary dyskinesia by disrupting assembly of ciliary dynein arms
por: Panizzi, Jennifer R., et al.
Publicado: (2012)

In vivo micro-scale tomography of ciliary behavior in the mammalian oviduct
por: Wang, Shang, et al.
Publicado: (2015)

Ultrastructural visualization of trans-ciliary rhodopsin cargoes in mammalian rods
por: Chuang, Jen-Zen, et al.
Publicado: (2015)

Wdpcp, a PCP Protein Required for Ciliogenesis, Regulates Directional Cell Migration and Cell Polarity by Direct Modulation of the Actin Cytoskeleton
por: Cui, Cheng, et al.
Publicado: (2013)

Podosome assembly is controlled by the GTPase ARF1 and its nucleotide exchange factor ARNO
por: Rafiq, Nisha Bte Mohd, et al.
Publicado: (2017)

Early steps in primary cilium assembly require EHD1- and EHD3-dependent ciliary vesicle formation
por: Lu, Quanlong, et al.
Publicado: (2015)

Heterotrimeric Kinesin-II Is Required for the Assembly of Motile 9+2 Ciliary Axonemes on Sea Urchin Embryos
por: Morris, Robert L., et al.
Publicado: (1997)

The Drosophila orthologue of the primary ciliary dyskinesia-associated gene, DNAAF3, is required for axonemal dynein assembly
por: zur Lage, Petra, et al.
Publicado: (2021)

p19(Arf) is required for the cellular response to chronic DNA damage
por: Bieging-Rolett, Kathryn T., et al.
Publicado: (2016)

The highly conserved FOXJ1 target CFAP161 is dispensable for motile ciliary function in mouse and Xenopus
por: Beckers, Anja, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_a117aidm32v8mkc58vt66og16r