Quantitative Genome-Wide Genetic Interaction Screens Reveal Global Epistatic Relationships of Protein Complexes in Escherichia coli

Large-scale proteomic analyses in Escherichia coli have documented the composition and physical relationships of multiprotein complexes, but not their functional organization into biological pathways and processes. Conversely, genetic interaction (GI) screens can provide insights into the biological...

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Detalles Bibliográficos
Autores principales: Babu, Mohan, Arnold, Roland, Bundalovic-Torma, Cedoljub, Gagarinova, Alla, Wong, Keith S., Kumar, Ashwani, Stewart, Geordie, Samanfar, Bahram, Aoki, Hiroyuki, Wagih, Omar, Vlasblom, James, Phanse, Sadhna, Lad, Krunal, Yeou Hsiung Yu, Angela, Graham, Christopher, Jin, Ke, Brown, Eric, Golshani, Ashkan, Kim, Philip, Moreno-Hagelsieb, Gabriel, Greenblatt, Jack, Houry, Walid A., Parkinson, John, Emili, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930520/
https://www.ncbi.nlm.nih.gov/pubmed/24586182
http://dx.doi.org/10.1371/journal.pgen.1004120

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