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Regulation of Mcl-1 by constitutive activation of NF-kappaB contributes to cell viability in human esophageal squamous cell carcinoma cells

BACKGROUND: Esophageal squamous cell carcinoma (ESCC) is one of the most lethal malignancies with a 5-year survival rate less than 15%. Understanding of the molecular mechanisms involved in the pathogenesis of ESCC becomes critical to develop more effective treatments. METHODS: Mcl-1 expression was...

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Detalles Bibliográficos
Autores principales: Liu, Haidan, Yang, Jinfu, Yuan, Yunchang, Xia, Zhenkun, Chen, Mingjiu, Xie, Li, Ma, Xiaolong, Wang, Jian, Ouyang, Sufeng, Wu, Qin, Yu, Fenglei, Zhou, Xinmin, Yang, Yifeng, Cao, Ya, Hu, Jianguo, Yin, Bangliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930545/
https://www.ncbi.nlm.nih.gov/pubmed/24529193
http://dx.doi.org/10.1186/1471-2407-14-98

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