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Discovery of genetic biomarkers contributing to variation in drug response of cytidine analogues using human lymphoblastoid cell lines

BACKGROUND: Two cytidine analogues, gemcitabine and cytosine arabinoside (AraC), are widely used in the treatment of a variety of cancers with a large individual variation in response. To identify potential genetic biomarkers associated with response to these two drugs, we used a human lymphoblastoi...

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Detalles Bibliográficos
Autores principales:	Li, Liang, Fridley, Brooke L, Kalari, Krishna, Niu, Nifang, Jenkins, Gregory, Batzler, Anthony, Abo, Ryan P, Schaid, Daniel, Wang, Liewei
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930546/ https://www.ncbi.nlm.nih.gov/pubmed/24483146 http://dx.doi.org/10.1186/1471-2164-15-93

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