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Quantitative Trait Loci Affecting Atherosclerosis at the Aortic Root Identified in an Intercross between DBA2J and 129S6 Apolipoprotein E-Null Mice
Apolipoprotein E-null mice on a DBA/2J genetic background (DBA-apoE) are highly susceptible to atherosclerosis in the aortic root area compared with those on a 129S6 background (129-apoE). To explore atherosclerosis-responsible genetic regions, we performed a quantitative trait locus (QTL) analysis...
Autores principales: | Kayashima, Yukako, Tomita, Hirofumi, Zhilicheva, Svetlana, Kim, Shinja, Kim, Hyung-Suk, Bennett, Brian J., Maeda, Nobuyo |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930552/ https://www.ncbi.nlm.nih.gov/pubmed/24586312 http://dx.doi.org/10.1371/journal.pone.0088274 |
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