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‘Death and Axes’: Unexpected Ca(2+) Entry Phenologs Predict New Anti-schistosomal Agents
Schistosomiasis is a parasitic flatworm disease that infects 200 million people worldwide. The drug praziquantel (PZQ) is the mainstay therapy but the target of this drug remains ambiguous. While PZQ paralyses and kills parasitic schistosomes, in free-living planarians PZQ caused an unusual axis dup...
Autores principales: | Chan, John D., Agbedanu, Prince N., Zamanian, Mostafa, Gruba, Sarah M., Haynes, Christy L., Day, Timothy A., Marchant, Jonathan S. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930560/ https://www.ncbi.nlm.nih.gov/pubmed/24586156 http://dx.doi.org/10.1371/journal.ppat.1003942 |
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