Reversible Silencing of Cytomegalovirus Genomes by Type I Interferon Governs Virus Latency

Herpesviruses establish a lifelong latent infection posing the risk for virus reactivation and disease. In cytomegalovirus infection, expression of the major immediate early (IE) genes is a critical checkpoint, driving the lytic replication cycle upon primary infection or reactivation from latency....

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Detalles Bibliográficos
Autores principales: Dağ, Franziska, Dölken, Lars, Holzki, Julia, Drabig, Anja, Weingärtner, Adrien, Schwerk, Johannes, Lienenklaus, Stefan, Conte, Ianina, Geffers, Robert, Davenport, Colin, Rand, Ulfert, Köster, Mario, Weiß, Siegfried, Adler, Barbara, Wirth, Dagmar, Messerle, Martin, Hauser, Hansjörg, Čičin-Šain, Luka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930589/
https://www.ncbi.nlm.nih.gov/pubmed/24586165
http://dx.doi.org/10.1371/journal.ppat.1003962

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