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Importin 7 and Nup358 Promote Nuclear Import of the Protein Component of Human Telomerase
In actively dividing eukaryotic cells, chromosome ends (telomeres) are subject to progressive shortening, unless they are maintained by the action of telomerase, a dedicated enzyme that adds DNA sequence repeats to chromosomal 3′end. For its enzymatic function on telomeres, telomerase requires nucle...
Autores principales: | Frohnert, Cornelia, Hutten, Saskia, Wälde, Sarah, Nath, Annegret, Kehlenbach, Ralph H. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930611/ https://www.ncbi.nlm.nih.gov/pubmed/24586428 http://dx.doi.org/10.1371/journal.pone.0088887 |
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