Excessive gestational weight gain over multiple pregnancies and the prevalence of obesity at age 40

OBJECTIVE: While several studies have found an association between excessive gestational weight gain and obesity later in life, to the best of our knowledge, no studies have explored the role of gestational weight gain events across the life course. DESIGN AND METHODS: We describe how the prevalence of mid-life obesity (BMI≥30 at age 40 or 41) among women varies by life course patterns of gestational weight gain (using 2009 IOM guidelines) in the USA’s National Longitudinal Survey of Youth 1979 cohort. RESULTS: Among women who reported 1–3 births before age 40, the prevalence of mid-life obesity increased with a rising number of excessive gestational weight gain events: from none (23.4%, n=875), to one (37.6%, n=707), to two (46.8%, n=427), and to three (54.6%, n=108), p<0.00005 for trend. Obesity prevalence was similar for the same number of excessive gestational weight gain events, regardless of parity. No clear pattern emerged for the sequencing of excessive gestational weight gain event(s) and later obesity. CONCLUSIONS: In our descriptive exploratory study, excessive gestational weight gain events appear to be associated with increased prevalence of obesity for parous women, suggesting the importance of preventive interventions regardless of timing of pregnancy-related weight changes over the life course.