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C. elegans CEP-1/p53 and BEC-1 Are Involved in DNA Repair
p53 is a transcription factor that regulates the response to cellular stress. Mammalian p53 functions as a tumor suppressor. The C. elegans p53, cep-1, regulates DNA-damage induced germline cell death by activating the transcription of egl-1 and ced-13. We used the C. elegans model to investigate ho...
Autores principales: | Hoffman, Sandy, Martin, Daniel, Meléndez, Alicia, Bargonetti, Jill |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930633/ https://www.ncbi.nlm.nih.gov/pubmed/24586407 http://dx.doi.org/10.1371/journal.pone.0088828 |
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