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Imbalanced Expression of Vcan mRNA Splice Form Proteins Alters Heart Morphology and Cellular Protein Profiles

The fundamental importance of the proteoglycan versican to early heart formation was clearly demonstrated by the Vcan null mouse called heart defect (hdf). Total absence of the Vcan gene halts heart development at a stage prior to the heart’s pulmonary/aortic outlet segment growth. This creates a pr...

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Detalles Bibliográficos
Autores principales:	Burns, Tara A., Dours-Zimmermann, Maria T., Zimmermann, Dieter R., Krug, Edward L., Comte-Walters, Susana, Reyes, Leticia, Davis, Monica A., Schey, Kevin L., Schwacke, John H., Kern, Christine B., Mjaatvedt, Corey H.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2014
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930639/ https://www.ncbi.nlm.nih.gov/pubmed/24586547 http://dx.doi.org/10.1371/journal.pone.0089133

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