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Effect of Darapladib Treatment on Endarterectomy Carotid Plaque Lipoprotein-Associated Phospholipase A(2) Activity: A Randomized, Controlled Trial

BACKGROUND: The aim of this study was to assess the effects of darapladib, a selective oral investigational lipoprotein-associated phospholipase A(2) inhibitor, on both plasma and plaque lipoprotein-associated phospholipase A(2) activity. METHODS: Patients undergoing elective carotid endarterectomy...

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Detalles Bibliográficos
Autores principales: Johnson, Joel L., Shi, Yi, Snipes, Rose, Janmohamed, Salim, Rolfe, Timothy E., Davis, Bill, Postle, Anthony, Macphee, Colin H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930668/
https://www.ncbi.nlm.nih.gov/pubmed/24586490
http://dx.doi.org/10.1371/journal.pone.0089034

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