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Up-Regulation of MicroRNA-190b Plays a Role for Decreased IGF-1 That Induces Insulin Resistance in Human Hepatocellular Carcinoma
BACKGROUND & AIMS: Insulin-like growth factor, (IGF)-1, is produced mainly by the liver and plays important roles in promoting growth and regulating metabolism. Previous study reported that development of hepatocellular carcinoma (HCC) was accompanied by a significant reduction in serum IGF-1 le...
Autores principales: | Hung, Tzu-Min, Ho, Cheng-Maw, Liu, Yen-Chun, Lee, Jia-Ling, Liao, Yow-Rong, Wu, Yao-Ming, Ho, Ming-Chih, Chen, Chien-Hung, Lai, Hong-Shiee, Lee, Po-Huang |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930738/ https://www.ncbi.nlm.nih.gov/pubmed/24586785 http://dx.doi.org/10.1371/journal.pone.0089446 |
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