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Successful neoadjuvant chemotherapy for large cell neuroendocrine carcinoma of the cervix: A case report()

• We present a case of cervical large cell neuroendocrine carcinoma (LCNEC) and neoadjuvant chemotherapy with irinotecan plus cisplatin that was extremely effective. • Cervical LCNEC is uncommon and highly aggressive, and optimal therapy has yet to be determined. • This case suggests that neoadjuvan...

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Detalles Bibliográficos
Autores principales: Omori, Makiko, Hashi, Akihiko, Kondo, Tetsuo, Tagaya, Hikaru, Hirata, Shuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930816/
https://www.ncbi.nlm.nih.gov/pubmed/24567884
http://dx.doi.org/10.1016/j.gynor.2013.12.001
Descripción
Sumario:• We present a case of cervical large cell neuroendocrine carcinoma (LCNEC) and neoadjuvant chemotherapy with irinotecan plus cisplatin that was extremely effective. • Cervical LCNEC is uncommon and highly aggressive, and optimal therapy has yet to be determined. • This case suggests that neoadjuvant chemotherapy followed by radical hysterectomy could be a useful treatment option for bulky cervical LCNEC.