High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()

A paediatric patient treated for acute lymphoblastic leukaemia developed cerebral abscesses caused by Aspergillus fumigatus. After surgical draining voriconazole treatment was started. The patient developed a Steven–Johnson syndrome and treatment was switched to L-AmB. The patient developed no new f...

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Detalles Bibliográficos
Autores principales: Brazzola, Pierluigi, Rossi, Mario R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2013
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930963/
https://www.ncbi.nlm.nih.gov/pubmed/24567890
http://dx.doi.org/10.1016/j.mmcr.2013.10.003
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author Brazzola, Pierluigi
Rossi, Mario R.
author_facet Brazzola, Pierluigi
Rossi, Mario R.
author_sort Brazzola, Pierluigi
collection PubMed
description A paediatric patient treated for acute lymphoblastic leukaemia developed cerebral abscesses caused by Aspergillus fumigatus. After surgical draining voriconazole treatment was started. The patient developed a Steven–Johnson syndrome and treatment was switched to L-AmB. The patient developed no new fungal lesions and L-AmB treatment was continued until the end of the therapy. Complete remission was achieved without neurological consequences. High dose L-AmB represents an alternative for secondary prophylaxis of invasive fungal infections in patients intolerant to azoles.
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spelling pubmed-39309632014-02-24 High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient() Brazzola, Pierluigi Rossi, Mario R. Med Mycol Case Rep Article A paediatric patient treated for acute lymphoblastic leukaemia developed cerebral abscesses caused by Aspergillus fumigatus. After surgical draining voriconazole treatment was started. The patient developed a Steven–Johnson syndrome and treatment was switched to L-AmB. The patient developed no new fungal lesions and L-AmB treatment was continued until the end of the therapy. Complete remission was achieved without neurological consequences. High dose L-AmB represents an alternative for secondary prophylaxis of invasive fungal infections in patients intolerant to azoles. Elsevier 2013-11-06 /pmc/articles/PMC3930963/ /pubmed/24567890 http://dx.doi.org/10.1016/j.mmcr.2013.10.003 Text en © 2013 The Authors http://creativecommons.org/licenses/by-nc-sa/3.0/ This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Article
Brazzola, Pierluigi
Rossi, Mario R.
High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()
title High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()
title_full High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()
title_fullStr High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()
title_full_unstemmed High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()
title_short High weekly doses of liposomal amphotericin B as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()
title_sort high weekly doses of liposomal amphotericin b as secondary prophylaxis after cerebral aspergillosis in a paediatric patient()
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3930963/
https://www.ncbi.nlm.nih.gov/pubmed/24567890
http://dx.doi.org/10.1016/j.mmcr.2013.10.003
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