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Significance of serum magnesium levels in critically ill-patients

BACKGROUND: Magnesium is one of the major electrolytes, deficiency of which is frequently overlooked in critical illness, leading to an adverse clinical outcome if not monitored regularly. SETTINGS AND DESIGN: Single center prospective observational study of 2 years duration. MATERIALS AND METHODS:...

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Autores principales: Zafar, Mir Sadaqat Hassan, Wani, Javaid Iqbal, Karim, Raiesa, Mir, Mohammad Muzaffer, Koul, Parvaiz Ahmad
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931212/
https://www.ncbi.nlm.nih.gov/pubmed/24600576
http://dx.doi.org/10.4103/2229-516X.125690
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author Zafar, Mir Sadaqat Hassan
Wani, Javaid Iqbal
Karim, Raiesa
Mir, Mohammad Muzaffer
Koul, Parvaiz Ahmad
author_facet Zafar, Mir Sadaqat Hassan
Wani, Javaid Iqbal
Karim, Raiesa
Mir, Mohammad Muzaffer
Koul, Parvaiz Ahmad
author_sort Zafar, Mir Sadaqat Hassan
collection PubMed
description BACKGROUND: Magnesium is one of the major electrolytes, deficiency of which is frequently overlooked in critical illness, leading to an adverse clinical outcome if not monitored regularly. SETTINGS AND DESIGN: Single center prospective observational study of 2 years duration. MATERIALS AND METHODS: The subjects studied were monitored for serum magnesium levels 2 times: Day 1 and day 4 of intensive care unit (ICU) admission. Patients were divided into normomagnesemic and hypomagnesemic groups and compared for various parameters. RESULTS: Out of 70 critically ill-patients, 50 patients (71.43%) were normomagnesemic, 17 patients (24.29%) were hypomagnesemic and three patients were hypermagnesemic. The stay of the patients in ICU (P > 0.05), Acute Physiology and Chronic Health Evaluation-II (APACHE-II) scoring (P = 0.34) and co-morbidity (P = 0.360) showed an insignificant variation between the two groups. Associated electrolyte abnormalities in hypomagnesemic patients were hypokalemia (58.82%), hyponatremia (47.05%), hypocalcemia (70.58%) and hypophosphatemia (29.41%). About 76.47% of hypomagnesemic population was on magnesium lowering drugs while as 46% of normomagnesemic population was on magnesium lowering drugs (P = 0.030). Mortality of hypomagnesemic group was 74.47% while that of normomagnesemic group was 36% (P = 0.004). CONCLUSION: Hypomagnesemia is a significant electrolyte abnormality in critically ill-patients. Critically ill hypomagnesemic patients have higher mortality than the normomagnesemic patients.
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spelling pubmed-39312122014-03-05 Significance of serum magnesium levels in critically ill-patients Zafar, Mir Sadaqat Hassan Wani, Javaid Iqbal Karim, Raiesa Mir, Mohammad Muzaffer Koul, Parvaiz Ahmad Int J Appl Basic Med Res Original Article BACKGROUND: Magnesium is one of the major electrolytes, deficiency of which is frequently overlooked in critical illness, leading to an adverse clinical outcome if not monitored regularly. SETTINGS AND DESIGN: Single center prospective observational study of 2 years duration. MATERIALS AND METHODS: The subjects studied were monitored for serum magnesium levels 2 times: Day 1 and day 4 of intensive care unit (ICU) admission. Patients were divided into normomagnesemic and hypomagnesemic groups and compared for various parameters. RESULTS: Out of 70 critically ill-patients, 50 patients (71.43%) were normomagnesemic, 17 patients (24.29%) were hypomagnesemic and three patients were hypermagnesemic. The stay of the patients in ICU (P > 0.05), Acute Physiology and Chronic Health Evaluation-II (APACHE-II) scoring (P = 0.34) and co-morbidity (P = 0.360) showed an insignificant variation between the two groups. Associated electrolyte abnormalities in hypomagnesemic patients were hypokalemia (58.82%), hyponatremia (47.05%), hypocalcemia (70.58%) and hypophosphatemia (29.41%). About 76.47% of hypomagnesemic population was on magnesium lowering drugs while as 46% of normomagnesemic population was on magnesium lowering drugs (P = 0.030). Mortality of hypomagnesemic group was 74.47% while that of normomagnesemic group was 36% (P = 0.004). CONCLUSION: Hypomagnesemia is a significant electrolyte abnormality in critically ill-patients. Critically ill hypomagnesemic patients have higher mortality than the normomagnesemic patients. Medknow Publications & Media Pvt Ltd 2014 /pmc/articles/PMC3931212/ /pubmed/24600576 http://dx.doi.org/10.4103/2229-516X.125690 Text en Copyright: © International Journal of Applied and Basic Medical Research http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Article
Zafar, Mir Sadaqat Hassan
Wani, Javaid Iqbal
Karim, Raiesa
Mir, Mohammad Muzaffer
Koul, Parvaiz Ahmad
Significance of serum magnesium levels in critically ill-patients
title Significance of serum magnesium levels in critically ill-patients
title_full Significance of serum magnesium levels in critically ill-patients
title_fullStr Significance of serum magnesium levels in critically ill-patients
title_full_unstemmed Significance of serum magnesium levels in critically ill-patients
title_short Significance of serum magnesium levels in critically ill-patients
title_sort significance of serum magnesium levels in critically ill-patients
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931212/
https://www.ncbi.nlm.nih.gov/pubmed/24600576
http://dx.doi.org/10.4103/2229-516X.125690
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