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Modulation of Wnt Activity and Cell Physiology by Butyrate in LT97 Microadenoma Cells

Dietary fiber intake is linked to a reduced risk of colon cancer. This effect may in part be due to butyrate, the fermentation product of fiber in the colon. Butyrate is a short-chain fatty acid that acts as a histone deacetylase inhibitor (HDACi). Butyrate induces apoptosis and represses clonal gro...

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Detalles Bibliográficos
Autores principales: Lazarova, Darina, Lee, Andrew, Wong, Terrence, Marian, Brigitte, Chiaro, Christopher, Rainey, Christian, Bordonaro, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Ivyspring International Publisher 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931268/
https://www.ncbi.nlm.nih.gov/pubmed/24563675
http://dx.doi.org/10.7150/jca.8569