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The effect of ROCK-1 activity change on the adhesive and invasive ability of Y79 retinoblastoma cells
BACKGROUND: Retinoblastoma (Rb) is the most common intraocular tumor in childhood worldwide. It is a deadly pediatric eye cancer. The main cause of death in Rb patients is intracranial and systemic metastasis. ROCK is the main downstream effector of Ras-homologous (Rho) family of GTPases which are i...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
BioMed Central
2014
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931292/ https://www.ncbi.nlm.nih.gov/pubmed/24528629 http://dx.doi.org/10.1186/1471-2407-14-89 |