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Exosomes Released by Islet-Derived Mesenchymal Stem Cells Trigger Autoimmune Responses in NOD Mice

Exosomes (EXOs) are secreted, nano-sized membrane vesicles that contain potent immunostimulatory materials. We have recently demonstrated that insulinoma-released EXOs can stimulate the autoimmune responses in nonobese diabetic (NOD) mice, a spontaneous disease model for type 1 diabetes. To investig...

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Detalles Bibliográficos
Autores principales: Rahman, Muhammad Jubayer, Regn, Danielle, Bashratyan, Roman, Dai, Yang D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Diabetes Association 2014
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931393/
https://www.ncbi.nlm.nih.gov/pubmed/24170696
http://dx.doi.org/10.2337/db13-0859