Cargando…
Sustained Inflammasome Activity in Macrophages Impairs Wound Healing in Type 2 Diabetic Humans and Mice
The hypothesis of this study was that sustained activity of the Nod-like receptor protein (NLRP)-3 inflammasome in wounds of diabetic humans and mice contributes to the persistent inflammatory response and impaired healing characteristic of these wounds. Macrophages (Mp) isolated from wounds on diab...
Autores principales: | Mirza, Rita E., Fang, Milie M., Weinheimer-Haus, Eileen M., Ennis, William J., Koh, Timothy J. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931398/ https://www.ncbi.nlm.nih.gov/pubmed/24194505 http://dx.doi.org/10.2337/db13-0927 |
Ejemplares similares
-
Nod-Like Receptor Protein-3 Inflammasome Plays an Important Role during Early Stages of Wound Healing
por: Weinheimer-Haus, Eileen M., et al.
Publicado: (2015) -
Blocking Interleukin-1β Induces a Healing-Associated Wound Macrophage Phenotype and Improves Healing in Type 2 Diabetes
por: Mirza, Rita E., et al.
Publicado: (2013) -
Low-Intensity Vibration Improves Angiogenesis and Wound Healing in Diabetic Mice
por: Weinheimer-Haus, Eileen M., et al.
Publicado: (2014) -
Foxo1 Inhibits Diabetic Mucosal Wound Healing but Enhances Healing of Normoglycemic Wounds
por: Xu, Fanxing, et al.
Publicado: (2015) -
Mast Cells Regulate Wound Healing in Diabetes
por: Tellechea, Ana, et al.
Publicado: (2016)