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Insulin Regulates the Unfolded Protein Response in Human Adipose Tissue
Endoplasmic reticulum (ER) stress is increased in obesity and is postulated to be a major contributor to many obesity-related pathologies. Little is known about what causes ER stress in obese people. Here, we show that insulin upregulated the unfolded protein response (UPR), an adaptive reaction to...
Autores principales: | Boden, Guenther, Cheung, Peter, Salehi, Sajad, Homko, Carol, Loveland-Jones, Catherine, Jayarajan, Senthil, Stein, T. Peter, Williams, Kevin Jon, Liu, Ming-Lin, Barrero, Carlos A., Merali, Salim |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Diabetes Association
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931405/ https://www.ncbi.nlm.nih.gov/pubmed/24130338 http://dx.doi.org/10.2337/db13-0906 |
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