One-Pot Asymmetric Nitro-Mannich/Hydroamination Cascades for the Synthesis of Pyrrolidine Derivatives: Combining Organocatalysis and Gold Catalysis

[Image: see text] The highly enantioselective preparation of trisubstituted pyrrolidine derivatives employing a one-pot nitro-Mannich/hydroamination cascade is reported. This cascade approach utilizes an asymmetric bifunctional organocatalytic nitro-Mannich reaction followed by a gold-catalyzed alle...

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Detalles Bibliográficos
Autores principales: Barber, David M., Ďuriš, Andrej, Thompson, Amber L., Sanganee, Hitesh J., Dixon, Darren J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2014
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931436/
https://www.ncbi.nlm.nih.gov/pubmed/24563809
http://dx.doi.org/10.1021/cs401008v

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