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Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression

We have previously identified a tyrosine kinase-independent, guanine nucleotide exchange factor (GEF) activity that is contained within the region of p210 BCR/ABL that distinguishes it from p190 BCR/ABL. In the current study we have compared the transforming activity of p190 BCR/ABL, p210 BCR/ABL, a...

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Detalles Bibliográficos
Autores principales: Tala, Ilona, Chen, Ru, Hu, Tinghui, Fitzpatrick, Ethan R, Williams, David A, Whitehead, Ian P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931524/
https://www.ncbi.nlm.nih.gov/pubmed/23207522
http://dx.doi.org/10.1038/leu.2012.351

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