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Contributions of the RhoGEF activity of p210 BCR/ABL to disease progression
We have previously identified a tyrosine kinase-independent, guanine nucleotide exchange factor (GEF) activity that is contained within the region of p210 BCR/ABL that distinguishes it from p190 BCR/ABL. In the current study we have compared the transforming activity of p190 BCR/ABL, p210 BCR/ABL, a...
Autores principales: | Tala, Ilona, Chen, Ru, Hu, Tinghui, Fitzpatrick, Ethan R, Williams, David A, Whitehead, Ian P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3931524/ https://www.ncbi.nlm.nih.gov/pubmed/23207522 http://dx.doi.org/10.1038/leu.2012.351 |
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